Program
Cancer therapy-related cardiac dysfunction: Collaboration with Oncology
May 24, 2024 from 12:10pm MDT to 12:40pm MDT
Statement of purpose: The purpose of this abstract is to present the topic of cancer therapy-related cardiac dysfunction in women undergoing systemic therapy for HER 2 + breast cancer.
Description of the issue: Cancer therapy-related cardiac dysfunction (CTRCD) is a relatively common side effect of anthracycline and -2 targeted therapies affecting 9-20% of cancer survivors (Guglin, et al., 2019). CTRCD is a decrease in left ventricular ejection fraction (LVEF) by greater than 10% to an abnormal value, generally less than 53 % (Lyon, et al., 2022). The incidence of CTRCD can vary depending on the patient’s cardiac risk factors and cancer therapies. An overview of the risk factors, pathophysiology, diagnostics, treatment, and surveillance of CTRCD will be presented. Future directions in the nursing management of CTRCD will be reviewed.
Summary of conclusions: Collaboration between cardiology and oncology is critical in the early detection and treatment of CTRCD. Early identification and treatment of CTRCD and completion of cancer therapies can result in >80% of patients recovering their heart function (Thavendiranathan, et al., 2021).
Description of significance and implications for practice. This early identification and treatment of CTRCD allow patients to continue their potentially cardiotoxic cancer therapies without interruption of treatment. Preventing interruptions in cancer therapies improves overall survival, decreases the risk of recurrence, and improves prognosis.